Protein Details: Potassium voltage-gated channel subfamily V member 2

Protein ID

ICDB_Pro_1233

Protein Name

Potassium voltage-gated channel subfamily V member 2

Gene Name

Kcnv2

Organism

Mus musculus (Mouse)

Length

562 amino acids

AlphaFoldDB

AF-Q8CFS6-F1-model_v4.pdb

Function

Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values (By similarity)

Sequence

MLKQSNERRWSLSYKPWSTPETEDVPNTGSNQHRRSICSLGARTGSQASIAPQWTEGNYNYYIEEDEDCGEEGEDWKDDLAEENQKAECLTSLLDGHNDTPAQMSTLKVNVGGHSYLLECCELANYPKTRLGRLATSTTRRGQLGLCDDYEAQTDEYFFDRDPAVFQLIYNFYTSGVLLVRDELCPRSFLEELGYWGVRLKYTPRCCRICFEERRDELSEQLKIQRELRAQAQAEEAEELFRDMRFYGPQRQRLWNLMEKPFSSVAAKAMGVATNLFVLISVVALALNTVEEMQHQAEQGTGGGDPRPILEHVEMLCVAFFTLEFLLRLASTPNLQRFARSALNLVDLVAILPFYLQLLLECFTSEDQRHNKDSPREHDLETVGRVGKVGQVLRIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLMLFITMGIFSFSAAVYSVEHDVPGTNFTSILHAWWWAAVSISTVGYGDMYPETHLGRLFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEYTAIRRERGKVNFMQRATKKMAECLSESHAQSTTRQEN

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1152/jn.00493.2007; 10.1101/gr.2596504

RefSeq

NP_899002.1